Throughout his life, a person often encounters the negative effects of microbes on the body. Bacterial pathogens can settle on the skin, in the gastrointestinal tract, in the genitourinary organs and even on the conjunctiva of the eye. In such a situation, only a strong antibacterial agent will help cope with the infection. Most often, treatment begins with medications based on ciprofloxacin, so doctors often prescribe the antibiotic Tsiprolet to patients. Next we will talk about the beneficial properties of this medication.
Release form
Tsiprolet is produced by many pharmaceutical companies, as it is one of the most popular antibacterial agents. It is produced in the following dosage forms:
- infusion solution - in polyethylene bottles of 100 ml, where the content of ciprofloxacin does not exceed 2 mg per ml;
- tablets - each containing 250 mg or 500 mg of the main active ingredient, they are packaged in blisters of 10 pieces;
- eye drops - sold in bottles with a dropper of 5-10 ml, which contain 3 mg of ciprofloxacin per 1 ml of solution.
According to the instructions for use of Tsiprolet 500, these tablets contain the maximum dose of the active substance. They are used to treat severe bacterial lesions in advanced infections.
Quick help for a panic attack
Benzodiazepine tranquilizers
The most effective and fastest-acting medications for panic attacks are a group of benzodiazepine tranquilizers
. These include:
- alprazolam (Xanax),
- clonazepam,
- diazepam (Relanium),
- bromodihydrochlorophenylbenzodiazepine (phenazepam).
These are potent drugs and therefore are not commercially available. They can be purchased using special prescriptions, which can only be prescribed by certified doctors in licensed clinics.
The action of benzodiazepine tranquilizers provides rapid relief of anxiety, vegetative manifestations (rapid pulse and breathing, sweating, trembling, chills and heat waves, dizziness, etc.), normalization of sleep and appetite.
Since the basis of any panic attack is anxiety and excessive activation of brain structures responsible for the protective anxiety reflex, then, regardless of the causes, mechanism of development and manifestation of panic, tranquilizers always have a quick effect. They will either prevent the development of a panic attack, or (if it has already begun) stop it.
Benzodiazepine tranquilizers are used once - as an ambulance, or in short courses (usually no more than a week). With long-term use, dependence is formed, one of the manifestations of which will be “increasing tolerance” - the need to increase the dose to achieve an effect.
These drugs are often used in tablet form. As a rule, taking one tranquilizer tablet ensures the development of a therapeutic effect in 20-40 minutes.
Some of these drugs (diazepam, bromodihydrochlorophenylbenzodiazepine) exist in the form of a solution, which allows them to be used as injections intramuscularly or intravenously, in which case the effect occurs very quickly - from a few seconds to several minutes.
Advantages of benzodiazepine tranquilizers: pronounced anti-anxiety effect, rapid onset of action, well tolerated.
Disadvantages: difficult to purchase (you need a doctor's prescription, a special prescription form), a common side effect is drowsiness and lethargy; if taken regularly, they can cause physical and mental dependence.
Non-benzodiazepine tranquilizers
The next group is non-benzodiazepine tranquilizers
. They are distinguished from the first group by a different chemical structure. The most common representatives:
- hydroxyzine (atarax),
- mebicar,
- etifoxine,
- meprobamate.
In terms of potency, they are inferior to the drugs of the previous group. But they also have their advantages: they are well tolerated, do not cause drowsiness, do not develop dependence, and are easier to purchase in pharmacies (no special prescriptions are needed).
The most common remedy in this group is ATARAX
. They can be used once to prevent or relieve a panic attack. It is also used for long-term use, which can prevent the recurrence of a panic attack.
Thus, tranquilizers
- the most common and popular group of pills for panic attacks. It has been noticed that many people who have long gotten rid of panic attacks, but remember these unpleasant anxiety states, try to carry a tranquilizer pill with them “just in case.”
Neuroleptics
Neuroleptics with sedative action. This is the next group of drugs that have a sedative effect and can relieve a panic attack. The most common tablets are:
- Thioridazine (Sonapax);
- Periciazine (neuleptil);
- Chlorprothixene (Truxal);
- Quetiapine (Seroquel);
- Alimemazine (teraligen);
- Sulpiride (eglonil).
The general sedative effect of these drugs allows, when taken continuously, to prevent the development of panic attacks, and when taken once, to relieve a panic attack.
The disadvantage of this group of drugs is that, in addition to anxiety, other emotional reactions (joy, surprise, delight, pleasure, curiosity, melancholy, etc.) can be suppressed.
Antidepressants with sedative effects
Despite the fact that antidepressants are the most prescribed pills in the complex treatment of panic attacks, they can also be used as an “ambulance” - once to stop a panic attack. For this purpose the following are most often used:
- Amitriptyline;
- Clomipramine (Anafranil);
- Mianserin (lerivon)
Unlike antipsychotics and tranquilizers, the effect of antidepressants does not develop as quickly, but is longer lasting.
Other drugs for quick relief of an attack
- aminophenylbutyric acid (phenibut),
- glycine,
- ethyl alcohol (alcohol),
- valocordin or corvalol (and their analogues),
- beta-blockers (anaprilin, atenolol),
- alpha-blockers (clinidine), etc.
Mechanism of action of the drug
Tsiprolet belongs to the group of fluoroquinolones and is an antibacterial drug with a wide range of effects. Its main active ingredient is ciprofloxacin. This chemical compound has the ability to penetrate the DNA structure of the cells that cause the infection, thereby disrupting the vital functions of bacteria, their ability to subsequently reproduce and develop. The result of this influence is the death of harmful microorganisms.
Tsiprolet tablets have a complex effect, effectively destroying microbes that are both at the reproduction stage and in the resting phase. The spectrum of negative effects of this medicine extends to almost all types of gram-positive and gram-negative bacteria, most of the anaerobic pathogens. The instructions for use of Tsiprolet state that its main active component actively eliminates bacterial microflora that are resistant to other antibiotics, for example, the nitrofuran or sulfonamide series. Resistance of microbes to this medicine appears only after a long period of time.
Indications
Ciprofan tablets - what do they help with? This antibiotic is used for the treatment of complicated or uncomplicated bacterial infections that are caused by strains of microorganisms sensitive to ciprofloxacin. The remedy is indicated for the following diseases:
- urinary tract infections;
- bacterial lesions of the gastrointestinal tract;
- sepsis;
- pathologies of ENT organs, especially in case of infection with staphylococcal microflora and gram-negative bacteria, including the Pseudomonas type;
- peritonitis;
- infectious lesions of the respiratory system (for example, pneumonia), if they are caused by Enterobacter, Staphylococcus, Klebsiella, Haemophilus influenzae, Legionella or microbes of the Branhamella, Pseudomonas species;
- inflammatory infectious diseases of the genital organs in men and women (prostatitis, adnexitis);
- infections of the musculoskeletal system and skin;
- some sexually transmitted diseases (gonorrhea);
- bacterial lesions of the eyelid and conjunctiva of the eyes;
- therapy and prevention of infections in patients with low immunity (for example, with neutropenia or after treatment with immunosuppressive drugs).
Comparison of addiction between Tsiprolet A and Tsiprolet
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “syndrome o” in Tsiprolet A is quite similar to the similar values in Tsiprolet. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Tsiprolet A the values of “syndrome o” are quite small, however, the same as in Tsiprolet.
Dosage and methods of application
The antibiotic Tsiprolet is prescribed by a doctor after examining the patient. The dose of the drug is selected based on the type of infection, the severity of the disease and the patient’s condition. The dosage regimen is also influenced by the functional ability of the urinary organs and the person’s body weight (when used in adolescence and childhood).
For the most severe cases of infection and when it is impossible to take the medication in tablet form, Tsiprolet is prescribed in the form of infusion solutions. Then the intravenous infusions of the drug are gradually stopped, and the patient switches to internal administration of the medication. The tablets do not need to be chewed; they simply need to be swallowed whole and washed down with a small amount of water. Take Tsiprolet, regardless of food intake, 500-750 mg twice a day.
The duration of therapy depends on the severity of the pathology and can vary from 3 to 21 days. Usually the doctor prescribes the use of this antibiotic for a period of 7 to 14 days.
Adverse reactions and contraindications for use
Tsiprolet very rarely causes allergic reactions. After treatment with this medication, the following side effects most often develop: dyspeptic disorders, nausea and vomiting, skin itching and rash, shortness of breath.
The use of this medicine is contraindicated in the following cases:
- during pregnancy;
- if you are allergic to ciprofloxacin and quinolone drugs;
- in adolescence and childhood;
- during lactation.
Tsiprolet is prescribed with caution to elderly patients. The medication is used only in special cases for people suffering from epilepsy, vascular pathologies, and organic diseases of the brain. Such patients are more likely to experience side effects due to taking the drug, so this antibiotic is indicated for them only in life-threatening situations. In case of allergic reactions and other complaints (for example, joint pain, myalgia), use of the medicine should be discontinued.
Special information
Tsiprolet is not effective against streptococci, so it is not prescribed for the treatment of pathologies caused by bacteria of this group. In case of severe infection by anaerobes and staphylococcal microflora, it is better to take the medication in combination with other antibiotics, which will help enhance the therapeutic effect of ciprofloxacin.
The instructions for Tsiprolet tablets indicate that this drug can have an effect on the patient’s body, changing the ability to concentrate. Therefore, it should not be used by transport drivers and persons servicing complex mechanisms and machines. It is unacceptable to use the medication in combination with alcohol. Tsiprolet is available only with a doctor's prescription.
Comparison of the effectiveness of Tsiprolet A and Tsiprolet
Tsiprolet A is more effective than Tsiprolet - this means that the ability of the medicinal substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Tsiprolet A is more pronounced, then it is impossible to achieve this effect with Tsiprolet even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Tsiprolet A and Tsiprolet are also different, as is bioavailability - the amount of a medicinal substance reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
